Phenol, 4-[(7-chloro-4-quinolinyl)aMino]-2-[(ethyl-d5-aMino)Methyl]- - Names and Identifiers
Phenol, 4-[(7-chloro-4-quinolinyl)aMino]-2-[(ethyl-d5-aMino)Methyl]- - Physico-chemical Properties
Molecular Formula | C18H13ClD5N3O
|
Molar Mass | 332.84 |
Melting Point | 179-181°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Pale Yellow to Brown |
Storage Condition | -20°C |
Phenol, 4-[(7-chloro-4-quinolinyl)aMino]-2-[(ethyl-d5-aMino)Methyl]- - Risk and Safety
Hazard Symbols | T - Toxic
|
Risk Codes | R25 - Toxic if swallowed
R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
Phenol, 4-[(7-chloro-4-quinolinyl)aMino]-2-[(ethyl-d5-aMino)Methyl]- - Introduction
N-Desethyl Amodiaquine-d5 (N-Desethyl Amodiaquine-d5) is a drug molecule that is a metabolite of the amofuran antimalarial drug amofuranine (Amodiaquine). It is chemically stable and has an accurate molecular weight. This compound is commonly used in scientific research and pharmacokinetic studies.
The primary use of N-Desethyl Amodiaquine-d5 is in the analysis of metabolites of aminofuran antimalarials in in vivo and in vitro studies. It can be used to understand the metabolic pathway of drugs in the human body, the role of metabolic enzymes and the study of related pharmacokinetic parameters. In addition, it can be used in drug interaction studies as well as in other areas of drug metabolism.
The preparation method of N-Desethyl Amodiaquine-d5 usually involves the synthesis of aminofuran antimalarial drug aminofuran quinoline, and then forms its metabolites in vivo or in vitro through metabolic reactions. Synthetic methods can vary according to specific needs, and analysis and purification are required to obtain high-purity products.
Regarding safety information, since N-Desethyl Amodiaquine-d5 are compounds used for scientific research, there is a lack of available detailed safety data. However, as a drug metabolite, its toxicity and side effects may be similar to those of amofuran antimalarials. When used, it is necessary to follow appropriate laboratory procedures and perform under conditions that meet safe operating standards. Before any use, it is recommended to consult a professional chemist or laboratory supervisor for more detailed and personalized safety information.
Last Update:2024-04-09 21:22:08